Ketamine-propofol (ketofol) in procedural sedation: a narrative review

J Dent Anesth Pain Med. 2023 Jun;23(3):123-133. doi: 10.17245/jdapm.2023.23.3.123. Epub 2023 May 26.

Abstract

Sedation methods for dental treatment are increasingly explored. Recently, ketofol, which is a combination of ketamine and propofol, has been increasingly used because the advantages and disadvantages of propofol and ketamine complement each other and increase their effectiveness. In this review, we discuss the pharmacology of ketamine and propofol, use of ketofol in various clinical situations, and differences in efficacy between ketofol and other sedatives.

Keywords: Dentistry; Ketamine; Ketofol; Procedural Sedation; Propofol.

Publication types

  • Review