Comparison of clinical cure rates from footrot and contagious ovine digital dermatitis using zinc sulphate foot bathing and topical oxytetracycline: A randomised trial

Vet Rec. 2023 Sep 20;193(6):e3116. doi: 10.1002/vetr.3116. Epub 2023 Jun 12.

Abstract

Background: This study reports the clinical cure rates of topical oxytetracycline and 10% zinc sulphate foot bathing for treatment of interdigital dermatitis (ID), footrot (FR) and contagious ovine digital dermatitis (CODD) in lambs.

Methods: The study was a randomised controlled trial of 75 lambs. Group A (n = 38) was foot bathed daily for 5 days in 10% zinc sulphate for 15 minutes and group B was treated with daily topical oxytetracycline for 5 days. On days 0, 7, 14, 28 and 42, lambs were scored for locomotion and foot lesions were recorded.

Results: The initial cure rates for ID were 96.20% and 97.00%; for FR, 100% and 95%; and for CODD, 90.09% and 83.33% for zinc sulphate and oxytetracycline, respectively. By day 42, these had changed to 53.16% and 61% for ID; 47.82% and 70% for FR; and 100% and 83.33% for CODD. There were no significant differences in cure rates between the treatments for most time points.

Limitations: The sample size was small, and further studies in larger cohorts and different classes of sheep are required before the findings can be translated into recommendations for clinical practice.

Conclusion: Both treatments achieved cure rates that are comparable to reported cure rates using systemic antibiotics and could be an effective alternative.

Keywords: contagious ovine digital dermatitis; footbath; footrot; interdigital dermatitis; lameness; oxytetracycline; sheep; treatment; zinc sulphate.

Publication types

  • Randomized Controlled Trial, Veterinary

MeSH terms

  • Animals
  • Digital Dermatitis* / drug therapy
  • Foot Rot* / drug therapy
  • Foot Rot* / prevention & control
  • Oxytetracycline* / therapeutic use
  • Sheep
  • Sheep Diseases* / drug therapy
  • Sheep Diseases* / pathology
  • Sheep Diseases* / prevention & control
  • Zinc Sulfate / therapeutic use

Substances

  • Zinc Sulfate
  • Oxytetracycline