A Smart Active Phase-Change Micropump Based on CMOS-MEMS Technology

Sensors (Basel). 2023 May 30;23(11):5207. doi: 10.3390/s23115207.

Abstract

The rational integration of many microfluidic chips and micropumps remains challenging. Due to the integration of the control system and sensors in active micropumps, they have unique advantages over passive micropumps when integrated into microfluidic chips. An active phase-change micropump based on complementary metal-oxide-semiconductor-microelectromechanical system (CMOS-MEMS) technology was fabricated and studied theoretically and experimentally. The micropump structure is simple and consists of a microchannel, a series of heater elements along the microchannel, an on-chip control system, and sensors. A simplified model was established to analyze the pumping effect of the traveling phase transition in the microchannel. The relationship between pumping conditions and flow rate was examined. Based on the experimental results, the maximum flow rate of the active phase-change micropump at room temperature is 22 µL/min, and long-term stable operation can be achieved by optimizing heating conditions.

Keywords: CMOS-MEMS; active micropump; phase-change micropump.

MeSH terms

  • Micro-Electrical-Mechanical Systems* / instrumentation
  • Micro-Electrical-Mechanical Systems* / methods
  • Microfluidic Analytical Techniques* / instrumentation
  • Microfluidic Analytical Techniques* / methods
  • Microfluidics / instrumentation
  • Microfluidics / methods
  • Oxides / chemistry
  • Semiconductors

Substances

  • Oxides

Grants and funding

This research received no external funding.