A novel fluorescence probe for the recognition of Cd2+ and its application

Yuntong Huang; Weizhong Chen; Mingyou Dong; Nana Li; Lianghui Chen; Li Ling; Qijiang Xu; Min Lin; Zhiyong Xing

doi:10.1016/j.saa.2023.122979

A novel fluorescence probe for the recognition of Cd²⁺ and its application

Spectrochim Acta A Mol Biomol Spectrosc. 2023 Nov 15:301:122979. doi: 10.1016/j.saa.2023.122979. Epub 2023 Jun 4.

Authors

Yuntong Huang¹, Weizhong Chen², Mingyou Dong³, Nana Li⁴, Lianghui Chen⁵, Li Ling¹, Qijiang Xu⁶, Min Lin², Zhiyong Xing⁷

Affiliations

¹ School of Laboratory Medicine, Youjiang Medical University for Nationalities, Baise, Guangxi 533000, China.
² Department of Medical Laboratory, Chaozhou People's Hospital Affiliated to Shantou University Medical College, Chaozhou, Guangdong 521000, China.
³ School of Laboratory Medicine, Youjiang Medical University for Nationalities, Baise, Guangxi 533000, China; Modern Industrial College of Biomedicine and Great Health, Youjiang Medical University for Nationalities, Baise, Guangxi 533000, China.
⁴ Department of Chemistry, Xinzhou Teachers University, Xinzhou, Shanxi 034000, China.
⁵ Modern Industrial College of Biomedicine and Great Health, Youjiang Medical University for Nationalities, Baise, Guangxi 533000, China.
⁶ School of Laboratory Medicine, Youjiang Medical University for Nationalities, Baise, Guangxi 533000, China; Modern Industrial College of Biomedicine and Great Health, Youjiang Medical University for Nationalities, Baise, Guangxi 533000, China. Electronic address: qijiangxu@126.com.
⁷ School of Laboratory Medicine, Youjiang Medical University for Nationalities, Baise, Guangxi 533000, China; Modern Industrial College of Biomedicine and Great Health, Youjiang Medical University for Nationalities, Baise, Guangxi 533000, China. Electronic address: zyxing@ymun.edu.cn.

PMID: 37295381
DOI: 10.1016/j.saa.2023.122979

Abstract

A facile fluorescence probe BQBH was synthesized and investigated on its spectrum property. The result showed that the BQBH had high sensitivity and selectivity for Cd²⁺ with lowest detection determined as 0.14 μM by fluorescence response. The 1: 1 binding ratio between BQBH and Cd²⁺ was determined by Job's plot, and the binding details were further confirmed by ¹H NMR titration, FT-IR spectrum and HRMS analysis. The applications including on test paper, smart phone and cell image were all also investigated.

Keywords: Cd(2+); Cell image; Fluorescence; Recognition; Smart phone.

MeSH terms

Cadmium* / analysis
Fluorescent Dyes* / chemistry
Magnetic Resonance Spectroscopy
Spectroscopy, Fourier Transform Infrared

Substances

Fluorescent Dyes
Cadmium