Smartphone-assisted ratiometric sensing platform for on-site tetracycline determination based on europium functionalized luminescent Zr-MOF

Yijian Zhao; Meiyi Liu; Shuai Zhou; Zhiyu Yan; Jingsheng Tian; Qiaojuan Zhang; Zhiyi Yao

doi:10.1016/j.foodchem.2023.136449

Smartphone-assisted ratiometric sensing platform for on-site tetracycline determination based on europium functionalized luminescent Zr-MOF

Food Chem. 2023 Nov 1:425:136449. doi: 10.1016/j.foodchem.2023.136449. Epub 2023 Jun 1.

Authors

Yijian Zhao¹, Meiyi Liu¹, Shuai Zhou¹, Zhiyu Yan¹, Jingsheng Tian¹, Qiaojuan Zhang¹, Zhiyi Yao²

Affiliations

¹ Beijing Laboratory of Food Quality and Safety, College of Food Science and Nutritional Engineering, China Agricultural University, Beijing 100083, China.
² Beijing Laboratory of Food Quality and Safety, College of Food Science and Nutritional Engineering, China Agricultural University, Beijing 100083, China. Electronic address: yaozy@cau.edu.cn.

PMID: 37295213
DOI: 10.1016/j.foodchem.2023.136449

Abstract

Accurate on-site analysis of tetracycline (TC) is of great research value for ensuring food safety and estimating environmental pollution. Herein, a smartphone-based fluorescent platform for TC detectionhas been developed based on a europium functionalized metal-organic framework (Zr-MOF/Cit-Eu). Based on the inner filter and antenna effect between Zr-MOF/Cit-Eu and TC, the probe exhibited a ratiometric fluorescent response toward TC, resulting in an emission color change from blue to red. Excellent sensing performance was achieved with a detection limit of 3.9 nM, consistent with the linear operation spanning nearly four orders of magnitude. Subsequently, visual test strips based on Zr-MOF/Cit-Eu were prepared, possessing the potential for accurate testing of TC via RGB signals. Finally, the proposed platform was well applied in actual samples with satisfied recoveries (92.27 to 110.22%). This MOF-based on-site fluorescent platform holds great potential on constructing intelligent platform for visual and quantitative detection of organic contaminants.

Keywords: Fluorescence; Ratiometric; Smartphone; Tetracycline; Zr-MOF/Cit-Eu.

MeSH terms

Anti-Bacterial Agents / analysis
Europium*
Fluorescent Dyes
Smartphone*
Spectrometry, Fluorescence / methods
Tetracycline

Substances

Europium
Fluorescent Dyes
Tetracycline
Anti-Bacterial Agents