Impact of pandemics and disruptions to vaccination on infectious diseases epidemiology past and present

Hum Vaccin Immunother. 2023 Aug 1;19(2):2219577. doi: 10.1080/21645515.2023.2219577. Epub 2023 Jun 8.

Abstract

Infectious diseases are a leading cause of morbidity and mortality worldwide with vaccines playing a critical role in preventing deaths. To better understand the impact of low vaccination rates and previous epidemics on infectious disease rates, and how these may help to understand the potential impacts of the current coronavirus disease 2019 (COVID-19) pandemic, a targeted literature review was conducted. Globally, studies suggest past suboptimal vaccine coverage has contributed to infectious disease outbreaks in vulnerable populations. Disruptions caused by the COVID-19 pandemic have contributed to a decline in vaccination uptake and a reduced incidence in several infectious diseases; however, these rates have increased following the lifting of COVID-19 restrictions with modeling studies suggesting a risk of increased morbidity and mortality from several vaccine-preventable diseases. This suggests a window of opportunity to review vaccination and infectious disease control measures before we see further disease resurgence in populations and age-groups currently unaffected.

Keywords: COVID-19; Infectious disease; literature review; vaccination rates.

Publication types

  • Review

MeSH terms

  • COVID-19* / epidemiology
  • COVID-19* / prevention & control
  • Communicable Diseases* / epidemiology
  • Humans
  • Pandemics / prevention & control
  • Vaccination
  • Vaccines*

Substances

  • Vaccines

Grants and funding

Pfizer provided the funding for the study and for the manuscript.