Gut microbiota bridges dietary nutrients and host immunity

Sci China Life Sci. 2023 Nov;66(11):2466-2514. doi: 10.1007/s11427-023-2346-1. Epub 2023 Jun 5.

Abstract

Dietary nutrients and the gut microbiota are increasingly recognized to cross-regulate and entrain each other, and thus affect host health and immune-mediated diseases. Here, we systematically review the current understanding linking dietary nutrients to gut microbiota-host immune interactions, emphasizing how this axis might influence host immunity in health and diseases. Of relevance, we highlight that the implications of gut microbiota-targeted dietary intervention could be harnessed in orchestrating a spectrum of immune-associated diseases.

Keywords: amino acid; carbohydrate; gut microbiota; immunity; lipid; trace element; vitamin.

Publication types

  • Systematic Review
  • Review

MeSH terms

  • Diet
  • Gastrointestinal Microbiome* / physiology
  • Nutrients