Fighting pain: the structure of gabapentin and its binding site in the Ca_vα₂δ subunit

Nat Struct Mol Biol. 2023 Jun;30(6):717-719. doi: 10.1038/s41594-023-01013-8.

Authors

Laurent Ferron^#¹, Maria A Gandini^#¹, Gerald W Zamponi²

Affiliations

¹ Department of Clinical Neuroscience, Hotchkiss Brain Institute, Cumming School of Medicine, University of Calgary, Calgary, Canada.
² Department of Clinical Neuroscience, Hotchkiss Brain Institute, Cumming School of Medicine, University of Calgary, Calgary, Canada. zamponi@ucalgary.ca.

^# Contributed equally.

PMID: 37286823
DOI: 10.1038/s41594-023-01013-8

No abstract available

Publication types

Research Support, Non-U.S. Gov't

MeSH terms

Binding Sites
Calcium Channels* / chemistry
Gabapentin
Humans
Pain*
Protein Domains

Substances

Gabapentin
Calcium Channels