Dynamic catcher for stabilization of high-viscosity extrusion jets

R Bruce Doak; Robert L Shoeman; Alexander Gorel; Thomas R M Barends; Bogdan Marekha; Stefan Haacke; Stanislaw Nizinski; Ilme Schlichting

doi:10.1107/S1600576723003795

Dynamic catcher for stabilization of high-viscosity extrusion jets

J Appl Crystallogr. 2023 May 29;56(Pt 3):903-907. doi: 10.1107/S1600576723003795. eCollection 2023 Jun 1.

Authors

R Bruce Doak¹, Robert L Shoeman¹, Alexander Gorel¹, Thomas R M Barends¹, Bogdan Marekha^{1

2}, Stefan Haacke², Stanislaw Nizinski¹, Ilme Schlichting¹

Affiliations

¹ Department of Biomolecular Mechanisms, Max Planck Institute for Medical Research, Jahnstrasse 29, 69120 Heidelberg, Germany.
² Institut de Physique et Chimie des Matériaux de Strasbourg, University of Strasbourg - CNRS, Strasbourg, France.

Abstract

A 'catcher' based on a revolving cylindrical collector is described. The simple and inexpensive device reduces free-jet instabilities inherent to high-viscosity extrusion injection, facilitating delivery of microcrystals for serial diffraction X-ray crystallography.

Keywords: catcher; high-viscosity extrusion; injection; serial crystallography.

Grants and funding

The following funding is acknowledged: Max–Planck–Gesellschaft.