Genomic features, evolutionary patterns and minimal residual disease at surgical margins as novel prognostic/predictive biomarkers in locally advanced rectal cancer

Affiliations

• ¹ Department of Radiation Oncology, Shandong First Medical University and Shandong Academy of Medical Sciences, Shandong Cancer Hospital and Institute, Jinan, China.
• ² Shanghe County People's Hospital, Jinan, China.
• ³ Geneseeq Research Institute, Nanjing Geneseeq Technology Inc., Nanjing, China.
• ⁴ Department of Pathology, Shandong Cancer Hospital and Institute, Shandong First Medical University and Shandong Academy of Medical Sciences, Jinan, China.
• ⁵ Department of Pathology, The Affiliated Cancer Hospital of Zhengzhou University, Zhengzhou, China.
• ⁶ Department of Radiation Oncology, The Affiliated Cancer Hospital of Zhengzhou University, Zhengzhou, China.
• ⁷ Department of Radiation Oncology, The University of Texas MD Anderson Cancer Center, Houston, Texas, USA.
• ⁸ Department of Chemistry, Rice University, Houston, Texas, USA.
• ⁹ School of Medicine, Nankai University, Tianjin, China.
• ¹⁰ Department of Bio-therapeutic, the First Medical Center, Chinese PLA General Hospital, Beijing, China.
• ¹¹ School of Public Health, Nanjing Medical University, Nanjing, China.