Evolution of Pain Control for Adult Pectus Excavatum Repair

Ann Thorac Surg. 2024 Apr;117(4):829-837. doi: 10.1016/j.athoracsur.2023.04.044. Epub 2023 Jun 4.

Abstract

Background: Pain control after minimally invasive repair of pectus excavatum (MIRPE) can be challenging, especially in adult patients undergoing surgical repair. This study reviewed different analgesic modalities used over ≥10 years after pectus repair.

Methods: A retrospective analysis was performed of adult patients (≥18 years) who underwent uncomplicated primary MIRPE at a single institution from October 2010 to December 2021. Patients were classified by analgesic modality used: epidural, elastomeric continuous infusion subcutaneous catheters (SC-Caths), and intercostal nerve cryoablation. Comparisons among the 3 groups were performed.

Results: In total, 729 patients were included (mean age, 30.9 ±10.3 years; 67% male; mean Haller index, 4.9 ±3.0). Patients in the cryoablation group required significantly lower doses of morphine equivalents (P < .001) and had overall the shortest hospital stay (mean, 1.9 ±1.5 days; P < .001) with <17% staying >2 days (vs epidural at 94% and SC-Cath at 48%; P < .001). The cryoablation group had a lower incidence of ileus and constipation (P < .001) but a higher incidence of pleural effusion requiring thoracentesis (P = .024). Mean pain scores among groups were minor (<3), and differences were insignificant.

Conclusions: The use of cryoablation in conjunction with enhanced recovery pathways provided significant benefit to our patients undergoing MIRPE compared with previous analgesic modalities. These benefits included a decrease in length of hospital stay, a reduction of in-hospital opioid use, and a lower incidence of opioid-related complications associated with constipation and ileus. Further studies to assess additional potential benefits with long-term follow-up after discharge are warranted.

MeSH terms

  • Adult
  • Analgesics
  • Analgesics, Opioid / therapeutic use
  • Constipation
  • Female
  • Funnel Chest* / surgery
  • Humans
  • Ileus*
  • Male
  • Minimally Invasive Surgical Procedures
  • Pain, Postoperative / prevention & control
  • Retrospective Studies
  • Young Adult

Substances

  • Analgesics, Opioid
  • Analgesics