Safety Assessment of Polyglyceryl Fatty Acid Esters as Used in Cosmetics

Int J Toxicol. 2023 Aug;42(2_suppl):5S-101S. doi: 10.1177/10915818231174440. Epub 2023 Jun 6.

Abstract

The Expert Panel for Cosmetic Ingredient Safety (Panel) assessed the safety of 274 polyglyceryl fatty acid esters. Each of the esters in this group is a polyether comprising 2 to 20 glyceryl residues, end-capped by esterification with simple carboxylic acids, such as fatty acids. Most of these ingredients are reported to function in cosmetics as skin-conditioning agents and/or surfactants. The Panel reviewed the available data and considered conclusions from their relevant previous reports, and determined that these ingredients are safe in cosmetics in the present practices of use and concentration described in this safety assessment when formulated to be non-irritating.

Keywords: cosmetics, personal care products; polyglyceryl fatty acid esters; risk assessment; safety.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Consumer Product Safety*
  • Cosmetics* / toxicity
  • Esters / toxicity
  • Fatty Acids / toxicity
  • Risk Assessment

Substances

  • Fatty Acids
  • Cosmetics
  • Esters