Cell Therapy for Androgenetic Alopecia: Elixir or Trick?

Yongcui Mao; Pinyan Liu; Jiayun Wei; Ye Xie; Qiuxia Zheng; Rui Li; Jia Yao

doi:10.1007/s12015-023-10532-2

Cell Therapy for Androgenetic Alopecia: Elixir or Trick?

Stem Cell Rev Rep. 2023 Aug;19(6):1785-1799. doi: 10.1007/s12015-023-10532-2. Epub 2023 Jun 5.

Authors

Yongcui Mao¹, Pinyan Liu¹, Jiayun Wei¹, Ye Xie¹, Qiuxia Zheng¹, Rui Li¹, Jia Yao^{2

3}

Affiliations

¹ The First Clinical Medical College of Lanzhou University, Lanzhou, China.
² The First Clinical Medical College of Lanzhou University, Lanzhou, China. yaoj06@lzu.edu.cn.
³ Key Laboratory of Biotherapy and Regenerative Medicine of Gansu Province, Lanzhou, China. yaoj06@lzu.edu.cn.

Abstract

Androgenetic alopecia is the most common cause of hair loss aggravated by increased life pressure, tension, and anxiety. Although androgenetic alopecia (AGA) does not significantly effect physical health, it can have serious negative impact on the mental health and quality of life of the patient. Currently, the effect of medical treatment for AGA is not idealistic, stem cell-based regenerative medicine has shown potential for hair regrowth and follicle repair, but the long-term effect and mechanism of stem cell therapy is not quite explicit. In this review, we summarize the methods, efficacy, mechanism, and clinical progress of stem cell therapies for AGA by now, hope it will present a more comprehensive view in this topic.

Keywords: Androgenetic Alopecia; Cells Therapy; Conditioned Media; Stem Cells.

Publication types

Review
Research Support, Non-U.S. Gov't

MeSH terms

Alopecia* / therapy
Cell- and Tissue-Based Therapy
Hair
Humans
Quality of Life*
Stem Cells