Rhythmic auditory stimulation as a potential neuromodulator for Parkinson's disease

Yuko Koshimori; Michael H Thaut

doi:10.1016/j.parkreldis.2023.105459

Rhythmic auditory stimulation as a potential neuromodulator for Parkinson's disease

Parkinsonism Relat Disord. 2023 Aug:113:105459. doi: 10.1016/j.parkreldis.2023.105459. Epub 2023 Jun 1.

Authors

Yuko Koshimori¹, Michael H Thaut²

Affiliations

¹ Music and Health Science Research Collaboratory, Faculty of Music, University of Toronto, 90 Wellesley Street West, Toronto, ON, M5S 1C5, Canada. Electronic address: yuko.koshimori@utoronto.ca.
² Music and Health Science Research Collaboratory, Faculty of Music, University of Toronto, 90 Wellesley Street West, Toronto, ON, M5S 1C5, Canada. Electronic address: michael.thaut@utoronto.ca.

PMID: 37277293
DOI: 10.1016/j.parkreldis.2023.105459

Abstract

Auditory rhythm-based therapeutic interventions such as rhythmic auditory stimulation (RAS) are effective in improving gait and balance and preventing falls in idiopathic Parkinson's disease (PD). Research showing associated neuromodulatory effects of RAS on brain oscillations is also emerging. The neuromodulation may be induced by neural entrainment and cross-frequency oscillatory coupling. Auditory rhythm and RAS based interventions are potentially effective in improving other PD symptoms and can be extended to atypical parkinsonism.

Keywords: Atypical parkinsonism; Beta oscillation; Cross-frequency coupling; Deep brain stimulation; Entrainment; Parkinson's disease; Rehabilitation; Rhythmic auditory stimulation.

Publication types

Review
Research Support, Non-U.S. Gov't

MeSH terms

Acoustic Stimulation
Brain
Gait / physiology
Humans
Parkinson Disease* / therapy
Physical Therapy Modalities