Personalization of human body models and beyond via image registration

Front Bioeng Biotechnol. 2023 May 19:11:1169365. doi: 10.3389/fbioe.2023.1169365. eCollection 2023.

Abstract

Finite element human body models (HBMs) are becoming increasingly important numerical tools for traffic safety. Developing a validated and reliable HBM from the start requires integrated efforts and continues to be a challenging task. Mesh morphing is an efficient technique to generate personalized HBMs accounting for individual anatomy once a baseline model has been developed. This study presents a new image registration-based mesh morphing method to generate personalized HBMs. The method is demonstrated by morphing four baseline HBMs (SAFER, THUMS, and VIVA+ in both seated and standing postures) into ten subjects with varying heights, body mass indices (BMIs), and sex. The resulting personalized HBMs show comparable element quality to the baseline models. This method enables the comparison of HBMs by morphing them into the same subject, eliminating geometric differences. The method also shows superior geometry correction capabilities, which facilitates converting a seated HBM to a standing one, combined with additional positioning tools. Furthermore, this method can be extended to personalize other models, and the feasibility of morphing vehicle models has been illustrated. In conclusion, this new image registration-based mesh morphing method allows rapid and robust personalization of HBMs, facilitating personalized simulations.

Keywords: finite element human body model; image registration; mesh morphing; personalized simulations; traffic safety.

Grants and funding

The authors acknowledge the fundings from Vinnova (no. 2019-03386) and the Swedish Research Council (no. 2020-04724 and 2020-04496) for providing partial financial support to this project. Open access funding was provided by KTH Royal Institute of Technology.