Evaluation of chronic idiopathic tinnitus and its psychosocial triggers

Sherifa Ahmed Hamed; Fadia Ahmed Attiah; Mohamed Fawzy; Mohamed Azzam

doi:10.12998/wjcc.v11.i14.3211

Evaluation of chronic idiopathic tinnitus and its psychosocial triggers

World J Clin Cases. 2023 May 16;11(14):3211-3223. doi: 10.12998/wjcc.v11.i14.3211.

Authors

Sherifa Ahmed Hamed¹, Fadia Ahmed Attiah², Mohamed Fawzy², Mohamed Azzam³

Affiliations

¹ Department of Neurology and Psychiatry, Assiut University, Faculty of Medicine, Assiut 71516, Egypt. hamedsherifa@aun.edu.eg.
² Department of Neurology and Psychiatry, Assiut University, Faculty of Medicine, Assiut 71516, Egypt.
³ Department of Otolaryngology, Assiut University, Faculty of Medicine, Assiut 71516, Egypt.

Abstract

Background: The tinnitus susceptibility patterns in relation to different psychological and life stressors are unknown in different cultures.

Aim: To determine the comorbid psychosocial factors and behaviors associated with tinnitus and the predictors for the increase in its severity.

Methods: Participants were 230 adults (males = 70; females = 160; mean age = 38.6 ± 3.3). They underwent audiograms, speech discrimination and masking testing, and neuropsychiatric evaluation. Measures used for assessment included tinnitus handicap inventory, depression anxiety stress scale 21 (DASS-21), perceived stress scale (PSS), and insomnia severity index (ISI).

Results: Patients had mean duration of tinnitus of 11.5 ± 2.5 mo. They had intact hearing perception at 250-8000 Hz and 95 (41.3%) had aggravation of tinnitus loudness by masking noise. Decompensated tinnitus was reported in 77% (n = 177). The majority had clinically significant insomnia (81.3%), somatic symptoms (75%) other than tinnitus and perceived moderate (46.1%) and high (44.3%) stress to tinnitus. The severe/extremely severe symptoms of depression, anxiety and stress were reported in 17.4%, 35.7% and 44.3%, respectively. Patients with decom-pensated type had significantly higher scores for ISI (P = 0.001) and DASS-21 (depression = 0.02, anxiety = 0.01, stress = 0.001) compared to those with compensated tinnitus. Psychiatric interviewing showed that 35.7% had non-specific anxiety disorder, 17.4% had major depression, and 19.6% fulfilled the criteria of somatization disorder. Multivariate analysis showed that the only independent predictors for tinnitus severity were the duration of tinnitus [odd ratios (OR) = 0.832, 95%CI: 0.640-1.158; P = 0.001] and PSS (OR = 0.835, 95%CI: 0.540-1.125; P = 0.001) scores.

Conclusion: To the best of our knowledge, this is the first study in our culture to evaluate the causal relationship between psychological factors and tinnitus onset, severity and persistence. Tinnitus could be the earliest and dominant somatic symptom induced by life stressors and psychological vulnerabilities. Therefore, multidisciplinary consultation (psychologists, psychiatrists, and neurologists) is important to acknowledge among the audiologists and otolaryngologists who primarily consult patients.

Keywords: Anxiety; Chronic tinnitus; Idiopathic; Insomnia; Psychosocial factors; Somatization; Stress.