Relationship between lumbar facet joint osteoarthritis and comorbidities: A cross-sectional study in the Japanese community

Kenji Kobayashi; Koji Otani; Miho Sekiguchi; Kinshi Kato; Ryoji Tominaga; Shin-Ichi Konno

doi:10.1016/j.jos.2023.05.002

Relationship between lumbar facet joint osteoarthritis and comorbidities: A cross-sectional study in the Japanese community

J Orthop Sci. 2023 Jun 1:S0949-2658(23)00129-X. doi: 10.1016/j.jos.2023.05.002. Online ahead of print.

Authors

Kenji Kobayashi¹, Koji Otani², Miho Sekiguchi¹, Kinshi Kato¹, Ryoji Tominaga¹, Shin-Ichi Konno¹

Affiliations

¹ Department of Orthopaedic Surgery, Fukushima Medical University School of Medicine, Fukushima, Japan.
² Department of Orthopaedic Surgery, Fukushima Medical University School of Medicine, Fukushima, Japan. Electronic address: kotani@fmu.ac.jp.

PMID: 37270372
DOI: 10.1016/j.jos.2023.05.002

Abstract

Background: Few epidemiological studies have evaluated associations between lumbar facet joint (LFJ) osteoarthritis (OA) and comorbidities. This study aimed to investigate the prevalence of LFJ OA in a Japanese community population and associations between LFJ OA and underlying diseases, including lower extremity OA.

Methods: This epidemiological cross-sectional study evaluated LFJ OA in 225 Japanese community residents (81 males, 144 females; median age, 66 years) using magnetic resonance imaging (MRI). LFJ OA from L1-L2 to L5-S1 was evaluated using a 4-grade classification. Associations between LFJ OA and comorbidities were examined using multiple logistic regression analyses adjusting for age, sex, and body mass index.

Results: Prevalences of LFJ OA were 28.6% at L1-L2, 36.4% at L2-L3, 48.0% at L3-L4, 57.3% at L4-L5, and 44.2% at L5-S1. Males were significantly more likely to have LFJ OA at several spinal levels (L1-L2 45.7% vs 18.9%, p < 0.001; L2-L3 46.9% vs 30.6%, p < 0.05; L4-L5 67.9% vs 51.4%, p < 0.05). LFJ OA was present in 50.0% of residents <50 years old, 68.4% at 50-59 years old, 86.3% at 60-69 years old, and 85.1% at ≥70 years old. Multiple logistic regression analysis showed no associations between LFJ OA and comorbidities.

Conclusions: The prevalence of LFJ OA as evaluated by MRI was >85% at ≥60 years old and highest at the L4-L5 spinal level. Males were significantly more likely to have LFJ OA at several spinal levels. Comorbidities were not associated with LFJ OA.

Keywords: Comorbidity; Lumbar facet joint; Osteoarthritis; Prevalence.