Mandibular reconstruction in head and neck cancer: which is the gold standard?

Eur Arch Otorhinolaryngol. 2023 Sep;280(9):3953-3965. doi: 10.1007/s00405-023-08050-5. Epub 2023 Jun 3.

Abstract

Introduction: The aim of this study is to perform a systematic review to compare the outcomes of the different surgical options for mandibular reconstruction in head and neck cancer.

Material and methods: 93 articles were selected. Four groups were identified: titanium plate without flaps, titanium plate covered by soft tissue flap, bone tissue flaps and double flaps. We compared patients' characteristics, site of mandibulectomy, type of reconstruction and complications.

Results: 4697 patients were reported. The groups were not homogeneous regarding the type of defect and the treatment history. A significant difference in terms of post-operative complications was found between group 1 and group 2 (p < 0.00001), and between group 2 and group 3 (p < 0.00001). Total complications rate for group 4 was significantly higher when compared to group 3 (p < 0.00001), but no significant difference was found with group 2.

Conclusion: These results suggest that mandibular reconstruction using a microvascular bone flap is the best surgical option in patients without significant comorbidities.

Keywords: Head and neck cancer; Mandibular reconstruction; Microvascular free flaps; Oral cancer; Oral oncology.

Publication types

  • Systematic Review
  • Review

MeSH terms

  • Free Tissue Flaps*
  • Head and Neck Neoplasms* / surgery
  • Humans
  • Mandibular Reconstruction* / methods
  • Plastic Surgery Procedures*
  • Retrospective Studies
  • Surgical Flaps
  • Titanium

Substances

  • Titanium