Exploring the potential for children to act on antimicrobial resistance in Nepal: Valuable insights from secondary analysis of qualitative data

PLoS One. 2023 Jun 2;18(6):e0285882. doi: 10.1371/journal.pone.0285882. eCollection 2023.

Abstract

This study explores the perceived roles of children in antimicrobial resistance (AMR) in two sites across Nepal. AMR is a global challenge and underpinned by many complex behavioural drivers including how antimicrobial medicines are sourced and used. Because of this social dynamic, several research groups are using community engagement (CE) approaches to understand AMR at community level. However, most data negate the importance of children in behaviours linked to, and potentially driving AMR. In this study, authors apply secondary analysis methods to 10 transcripts representing the views of 23 adults engaged in an AMR-focused film-making project. By focusing on participants' reference to children, we reveal that antimicrobial usage and adherence to health providers' messages can be influenced by the age of the patient. Secondly that children are involved in some of the behaviours which are known to drive antimicrobial resistance such as purchasing over-the-counter antibiotic drugs. Finally, community members discuss that, with careful creation of resources, AMR could be meaningfully presented in educational settings with a view to children acting as agents of change around AMR-driving behaviours. Findings suggest that age-inclusive community engagement projects could be effective in tackling AMR at community level in Nepal and other low resource settings.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Adult
  • Anti-Bacterial Agents* / pharmacology
  • Anti-Bacterial Agents* / therapeutic use
  • Child
  • Drug Resistance, Bacterial*
  • Humans
  • Nepal
  • Nonprescription Drugs

Substances

  • Anti-Bacterial Agents
  • Nonprescription Drugs

Grants and funding

Grant Award number AH/T007915/1. Awarded to Jessica Mitchell January 2020 by the AHRC/GCRF Follow-on Funding Call. Original study funded by AH/R005869/1 awarded to Paul Cooke in 2017 by the AHRC. The funders had no role in study design, data collection and analysis, decision to publish, or preparation of the manuscript.