Comprehensive Review on Fabricating Bioactive Ceramic Bone Scaffold Using Vat Photopolymerization

ACS Biomater Sci Eng. 2023 Jun 12;9(6):3032-3057. doi: 10.1021/acsbiomaterials.3c00051. Epub 2023 Jun 1.

Abstract

In recent years, bioactive ceramic bone scaffolds have drawn remarkable attention as an alternative method for treating and repairing bone defects. Vat photopolymerization (VP) is a promising additive manufacturing (AM) technique that enables the efficient and accurate fabrication of bioactive ceramic bone scaffolds. This review systematically reviews the research progress of VP-printed bioactive ceramic bone scaffolds. First, a summary and comparison of commonly used bioactive ceramics and different VP techniques are provided. This is followed by a detailed introduction to the preparation of ceramic suspensions and optimization of printing and heat treatment processes. The mechanical strength and biological performance of the VP-printed bioactive ceramic scaffolds are then discussed. Finally, current challenges and future research directions in this field are highlighted.

Keywords: bioactive ceramic; bone scaffold; ceramic suspension; process optimization; vat photopolymerization.

Publication types

  • Review
  • Systematic Review
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Bone and Bones*
  • Ceramics / therapeutic use
  • Tissue Scaffolds*