Case Report: A case of Chlamydia psittaci infection in an HIV patient

Front Cell Infect Microbiol. 2023 May 16:13:1185803. doi: 10.3389/fcimb.2023.1185803. eCollection 2023.

Abstract

Chlamydia psittaci is the pathogen of psittacosis and infects a wide range of birds and even humans. Human infection occurs most commonly in those with a history of contact with birds or poultry. We describe a case of psittacosis in a human immunodeficiency virus infected patient in Zhejiang Province for the first time. C. psittaci infection was confirmed by nested polymerase chain reaction (PCR) and Real-Time PCR. Phylogenetic analysis revealed that the sequences from the patient's samples clustered with genotype A in the same branch. Our study highlights the possibility of diagnosing psittacosis in patients with a chronic disease such as HIV-infected patients, and should increase awareness and surveillance of psittacosis in China.

Keywords: Chlamydia psittaci; diagnosis; genotype; next-generation sequencing; psittacosis.

Publication types

  • Case Reports
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Animals
  • Birds / genetics
  • Chlamydophila psittaci* / genetics
  • HIV Infections* / complications
  • Humans
  • Phylogeny
  • Psittacosis* / complications
  • Psittacosis* / diagnosis
  • Psittacosis* / epidemiology
  • Real-Time Polymerase Chain Reaction

Grants and funding

This study was supported by Natural Science Foundation of Zhejiang Province (LGF20H260003) and Medical Science and Technology Program of Zhejiang Province (2020RC050).