Right-censored partially linear regression model with error in variables: application with carotid endarterectomy dataset

Int J Biostat. 2023 May 31. doi: 10.1515/ijb-2022-0044. Online ahead of print.

Abstract

This paper considers a partially linear regression model relating a right-censored response variable to predictors and an extra covariate with measured error. The main problem here is that censorship and measurement error problems need to be solved to estimate the model correctly. In this sense, we propose three modified semiparametric estimators obtained from local polynomial regression, kernel smoothing, and B-spline smoothing methods based on kernel deconvolution approach and synthetic data transformation. Here, kernel deconvolution technique is used to solve the measurement error problem in the model and synthetic data transformation is considered to add the effect of censorship to the estimation procedure, which is a very common method in the literature. The performances of the introduced estimators are compared in the detailed Monte-Carlo simulation study. In addition, Carotid endarterectomy data is used as real-world data example and results are presented. According to the results, it is seen that the deconvoluted local polynomial method gives more qualified estimates than other two methods.

Keywords: B-spline; deconvolution; kernel smoothing; local polynomial; synthetic data.