Is the Environmental Risk of Metformin Underestimated?

Unax Lertxundi; Saioa Domingo-Echaburu; Susana Barros; Miguel Machado Santos; Teresa Neuparth; Jose Benito Quintana; Rosario Rodil; Rosa Montes; Gorka Orive

doi:10.1021/acs.est.3c02468

Is the Environmental Risk of Metformin Underestimated?

Environ Sci Technol. 2023 Jun 13;57(23):8463-8466. doi: 10.1021/acs.est.3c02468. Epub 2023 May 31.

Authors

Unax Lertxundi¹, Saioa Domingo-Echaburu², Susana Barros^{3

4}, Miguel Machado Santos^{3

5}, Teresa Neuparth³, Jose Benito Quintana⁶, Rosario Rodil⁶, Rosa Montes⁶, Gorka Orive^{7

8

9

10

11}

Affiliations

¹ Bioaraba Health Research Institute, Osakidetza Basque Health Service, Araba Mental Health Network, Araba Psychiatric Hospital, Pharmacy Service, c/Alava 43, 01006 Vitoria-Gasteiz, Alava, Spain.
² Osakidetza Basque Health Service, Debagoiena Integrated Health Organisation, Pharmacy Service, Nafarroa Hiribidea 16, 20500 Arrasate, Gipuzkoa, Spain.
³ CIIMAR/CIMAR_LA - Interdisciplinary Centre of Marine and Environmental Research, Endocrine Disruptors and Emerging Contaminants Group, University of Porto, Avenida General Norton de Matos, S/N, 4450-208 Matosinhos, Portugal.
⁴ CITAB - Centre for the Research and Technology of Agro-Environmental and Biological Sciences, University of Trás-os-Montes and Alto Douro (UTAD), Quinta de Prados, Pavilhão 2, 5000-801 Vila Real, Portugal.
⁵ FCUP - Department of Biology, Faculty of Sciences, University of Porto, Rua do Campo Alegre s/n, 4169-007 Porto, Portugal.
⁶ Department of Analytical Chemistry, Nutrition and Food Sciences, IAQBUS - Institute of Research on Chemical and Biological Analysis, Universidade de Santiago de Compostela, Constantino Candeira S/N, 15782 Santiago de Compostela, Spain.
⁷ NanoBioCel Group, Laboratory of Pharmaceutics, School of Pharmacy, University of the Basque Country UPV/EHU, Paseo de la Universidad 7, Vitoria-Gasteiz 01006, Spain.
⁸ Biomedical Research Networking Centre in Bioengineering, Biomaterials and Nanomedicine (CIBER-BBN), Vitoria-Gasteiz 28029, Spain.
⁹ Bioaraba, NanoBioCel Research Group, 01006 Vitoria-Gasteiz, Spain.
¹⁰ University Institute for Regenerative Medicine and Oral Implantology - UIRMI (UPV/EHU-Fundación Eduardo Anitua), Vitoria 01007, Spain.
¹¹ Singapore Eye Research Institute, The Academia, 20 College Road, Discovery Tower, Singapore 169856.

PMID: 37256706
DOI: 10.1021/acs.est.3c02468

No abstract available

Keywords: pharmaceuticals in the environment; predicted no-effect concentration (PNEC); surface water; water framework directive.

MeSH terms

Environmental Monitoring
Fresh Water / analysis
Metformin*
Pharmaceutical Preparations
Risk Assessment
Water Pollutants, Chemical* / analysis

Substances

Metformin
Water Pollutants, Chemical
Pharmaceutical Preparations