Inflammatory myofibroblastic tumor of the thyroid gland

Front Endocrinol (Lausanne). 2023 May 15:14:1156117. doi: 10.3389/fendo.2023.1156117. eCollection 2023.

Abstract

Inflammatory myofibroblastic tumor (IMT) is a mesenchymal tumor with low incidence, which is extremely rare in the thyroid. At present, there is a lack of understanding regarding the etiology, pathogenesis, diagnosis and treatment of thyroid IMT. To improve the understanding of the disease, this article reviews the pathogenesis, clinical manifestations, pathology and immunohistochemistry, diagnosis, therapy and prognosis of thyroid IMT.

Keywords: ALK; inflammatory myofibroblastic tumor (IMT); rare tumor; spindle cell; thyroid gland.

Publication types

  • Review

MeSH terms

  • Anaplastic Lymphoma Kinase
  • Granuloma, Plasma Cell*
  • Humans
  • In Situ Hybridization, Fluorescence
  • Thyroid Neoplasms* / diagnosis
  • Thyroid Neoplasms* / surgery

Substances

  • Anaplastic Lymphoma Kinase