Mass cytometry uncovers a distinct peripheral immune profile and upregulated CD38 expression in patients with hidradenitis suppurativa

Peter Dimitrion; Iltefat Hamzavi; Congcong Yin; Jugmohit Toor; Kalpana Subedi; Namir Khalasawi; Angela Miller; Richard Huggins; Indra Adrianto; Jesse Veenstra; Gautham Vellaichamy; Aakash Hans; Steven Daveluy; Mohammad Athar; Wilson Liao; Henry Lim; David Ozog; Li Zhou; Qing-Sheng Mi

doi:10.1038/s41423-023-01037-6

Mass cytometry uncovers a distinct peripheral immune profile and upregulated CD38 expression in patients with hidradenitis suppurativa

Cell Mol Immunol. 2023 Aug;20(8):972-975. doi: 10.1038/s41423-023-01037-6. Epub 2023 May 29.

Authors

Peter Dimitrion^{1

2

3}, Iltefat Hamzavi¹, Congcong Yin^{1

2}, Jugmohit Toor^{1

2

3}, Kalpana Subedi^{1

2}, Namir Khalasawi^{1

2}, Angela Miller¹, Richard Huggins¹, Indra Adrianto^{1

2

4}, Jesse Veenstra^{1

2}, Gautham Vellaichamy¹, Aakash Hans^{1

2}, Steven Daveluy⁵, Mohammad Athar⁶, Wilson Liao⁷, Henry Lim¹, David Ozog¹, Li Zhou^{8

9

10}, Qing-Sheng Mi^{11

12

13

14}

Affiliations

¹ Center for Cutaneous Biology and Immunology Research, Department of Dermatology, Henry Ford Health System, Detroit, MI, 48202, USA.
² Immunology Research Program, Henry Ford Cancer Institute, Henry Ford Health System, Detroit, MI, 48202, USA.
³ Cancer Biology Graduate Program, School of Medicine, Wayne State University, Detroit, MI, 48202, USA.
⁴ Center for Bioinformatics, Department of Public Health Sciences, Henry Ford Health System, Detroit, MI, 48202, USA.
⁵ Department of Dermatology, Wayne State University School of Medicine, Detroit, MI, 48202, USA.
⁶ University of Alabama at Birmingham (UAB) Research Center of Excellence in Arsenicals, Department of Dermatology, University of Alabama at Birmingham, Birmingham, AL, USA.
⁷ Department of Dermatology, University of California San Francisco, San Francisco, CA, USA.
⁸ Center for Cutaneous Biology and Immunology Research, Department of Dermatology, Henry Ford Health System, Detroit, MI, 48202, USA. lzhou1@hfhs.org.
⁹ Immunology Research Program, Henry Ford Cancer Institute, Henry Ford Health System, Detroit, MI, 48202, USA. lzhou1@hfhs.org.
¹⁰ Department of Biochemistry, Microbiology, and Immunology, School of Medicine, Wayne State University, Detroit, MI, 48202, USA. lzhou1@hfhs.org.
¹¹ Center for Cutaneous Biology and Immunology Research, Department of Dermatology, Henry Ford Health System, Detroit, MI, 48202, USA. QMI1@hfhs.org.
¹² Immunology Research Program, Henry Ford Cancer Institute, Henry Ford Health System, Detroit, MI, 48202, USA. QMI1@hfhs.org.
¹³ Cancer Biology Graduate Program, School of Medicine, Wayne State University, Detroit, MI, 48202, USA. QMI1@hfhs.org.
¹⁴ Department of Biochemistry, Microbiology, and Immunology, School of Medicine, Wayne State University, Detroit, MI, 48202, USA. QMI1@hfhs.org.

PMID: 37248290
PMCID: PMC10387467 (available on 2024-08-01)
DOI: 10.1038/s41423-023-01037-6

No abstract available

Publication types

Letter
Research Support, N.I.H., Extramural
Research Support, Non-U.S. Gov't

MeSH terms

Hidradenitis Suppurativa*
Humans

Publication types

MeSH terms

Grants and funding