Metopic and Sagittal Craniosynostosis in Williams Syndrome

Sarut Chaisrisawadisuk; Inthira Khampalikit; Mark H Moore; Achara Sathienkijkanchai

doi:10.1097/SCS.0000000000009394

Metopic and Sagittal Craniosynostosis in Williams Syndrome

J Craniofac Surg. 2023 Sep 1;34(6):e564-e566. doi: 10.1097/SCS.0000000000009394. Epub 2023 May 29.

Authors

Sarut Chaisrisawadisuk¹, Inthira Khampalikit², Mark H Moore³, Achara Sathienkijkanchai⁴

Affiliations

¹ Division of Plastic Surgery, Department of Surgery, Faculty of Medicine Siriraj Hospital, Mahidol University, Bangkok, Thailand.
² Division of Neurosurgery, Department of Surgery, Faculty of Medicine Siriraj Hospital, Mahidol University, Bangkok, Thailand.
³ Cleft and Craniofacial South Australia, Women's and Children's Hospital, North Adelaide, South Australia, Australia.
⁴ Division of Medical Genetics, Department of Pediatrics, Faculty of Medicine Siriraj Hospital, Mahidol University, Bangkok, Thailand.

PMID: 37246286
DOI: 10.1097/SCS.0000000000009394

Abstract

Craniosynostosis has been previously reported in patients with Williams syndrome. Due to the associated significant cardiovascular anomalies, with an attendant increased risk of death under anaesthesia, most patients have been managed conservatively. Here we report the multidisciplinary approach in a 12-month-old female infant with Williams syndrome who has metopic and sagittal craniosynostosis. The child successfully underwent calvarial remodelling procedures, with the clinical outcome demonstrating dramatically improved global development after surgery.

MeSH terms

Child
Craniosynostoses* / complications
Craniosynostoses* / diagnostic imaging
Craniosynostoses* / surgery
Female
Humans
Infant
Jaw Abnormalities*
Retrospective Studies
Williams Syndrome* / complications
Williams Syndrome* / surgery