Vertebral osteomyelitis due to Mycobacterium abscessus subsp. massiliense with paravertebral abscess: A case report and review

J Infect Chemother. 2023 Sep;29(9):922-926. doi: 10.1016/j.jiac.2023.05.020. Epub 2023 May 25.

Abstract

The incidence of vertebral osteomyelitis (VO) caused by non-tuberculosis mycobacteria (NTM) without immunocompetence is extremely rare. Herein, we reported on a case of VO caused by NTM. A 38-year-old man was admitted to our hospital with persisting low back and leg pain which had lasted for a year. Before coming to our hospital, the patient was treated with antibiotics and iliopsoas muscle drainage. The biopsy confirmed the presence of a NTM, Mycobacterium abscessus subsp. massiliense. Several tests were conducted which showed the infection had progressively increased, such as vertebral endplate destruction on plain radiography, computed tomography scan, and epidural and paraspinal muscle abscesses on magnetic resonance imaging. The patient underwent radical debridement, anterior intervertebral fusion with bone graft, and posterior instrumentation with antibiotic administration. A year later, the patient's low back and leg pain was relieved without any analgetic. VO due to NTM is rare but can be treated with multimodal therapy.

Keywords: Infection; Mycobacterium abscessus subsp. massiliense; Non-tuberculosis mycobacteria; Spine; Vertebral osteomyelitis.

Publication types

  • Case Reports
  • Review

MeSH terms

  • Abscess / diagnosis
  • Adult
  • Anti-Bacterial Agents / therapeutic use
  • Humans
  • Male
  • Mycobacterium Infections, Nontuberculous* / diagnosis
  • Mycobacterium Infections, Nontuberculous* / drug therapy
  • Mycobacterium abscessus*
  • Nontuberculous Mycobacteria
  • Osteomyelitis* / drug therapy
  • Osteomyelitis* / therapy
  • Pain / drug therapy

Substances

  • Anti-Bacterial Agents