Evaluation of the Potential Diagnostic Utility of the Determination of Selected Immunological and Molecular Parameters in Patients with Ovarian Cancer

Diagnostics (Basel). 2023 May 12;13(10):1714. doi: 10.3390/diagnostics13101714.

Abstract

Ovarian cancer is one of the most serious challenges in modern gynaecological oncology. Due to its non-specific symptoms and the lack of an effective screening procedure to detect the disease at an early stage, ovarian cancer is still marked by a high mortality rate among women. For this reason, a great deal of research is being carried out to find new markers that can be used in the detection of ovarian cancer to improve early diagnosis and survival rates of women with ovarian cancer. Our study focuses on presenting the currently used diagnostic markers and the latest selected immunological and molecular parameters being currently investigated for their potential use in the development of new diagnostic and therapeutic strategies.

Keywords: adipocytokines; galectins; miRNA; ovarian cancer; potential biomarkers.

Publication types

  • Review

Grants and funding

This research was funded by Medical University of Silesia in Katowice, Poland, grant number PCN-1-069/K/1/O.