Diagnosing Disorders of Hypopigmentation and Depigmentation in Patients with Skin of Color

Dermatol Clin. 2023 Jul;41(3):407-416. doi: 10.1016/j.det.2023.02.006. Epub 2023 Mar 27.

Abstract

Skin hypopigmentation and depigmentation disorders are a top concern for patients with skin of color seeking care from a dermatologist. The visual contrast between involved and uninvolved skin in these disorders makes them particularly burdensome for patients with skin of color. These disorders may have a wide differential of diagnosis, as patients with skin of color may present differently or more frequently than White patients for certain conditions. Clues from a comprehensive history and physical examination with standard lighting and a Wood's light are essential for clinching the diagnosis, although a biopsy may be warranted in special cases.

Keywords: Depigmentation; Hypopigmentation; Medical dermatology; Skin of color.

Publication types

  • Review

MeSH terms

  • Diagnosis, Differential
  • Humans
  • Hypopigmentation* / diagnosis
  • Hypopigmentation* / etiology
  • Hypopigmentation* / pathology
  • Skin Pigmentation*