Diabetes and deaths of COVID-19 patients: Systematic review of meta-analyses

Aakriti Garg; Mahesh Kumar Posa; Anoop Kumar

doi:10.1016/j.hsr.2023.100099

Diabetes and deaths of COVID-19 patients: Systematic review of meta-analyses

Health Sci Rev (Oxf). 2023 Jun:7:100099. doi: 10.1016/j.hsr.2023.100099. Epub 2023 May 18.

Authors

Aakriti Garg¹, Mahesh Kumar Posa², Anoop Kumar³

Affiliations

¹ School of Pharmaceutical Sciences, Apeejay Stya University, Sohna, Gurugram 122103, India.
² School of Pharmacy and Technology Management, SVKM'S NMIMS, Polepally SEZ, Jadcherla, Hyderabad, 509301, India.
³ Department of Pharmacology, Delhi Institute of Pharmaceutical Sciences and Research (DIPSAR), Delhi Pharmaceutical Sciences & Research University (DPSRU) New Delhi 110017, India.

Abstract

Background: COVID-19 is affecting all kinds of patients including diabetics. This article provides an overview of conducted meta-analyses regarding the effect of diabetes on the deaths of COVID-19 patients.

Methodology: The study was conducted as per preferred reporting items for systematic reviews and meta-analysis (PRISMA) statement.

Data sources: The relevant meta-analyses were searched on PubMed till April 2021 and data was extracted from 24 relevant meta-analyses. The overall estimate was calculated in terms of odds ratio or relative risk with a 95% confidence interval.

Results: A total of 09 meta-analyses showed the association of diabetes with the death of COVID-19 patients and 15 meta-analyses have reported the association of diabetes with other comorbidities in the death of COVID-19 patients. The pooled odds ratio or relative risk has shown a significant association of diabetes alone or its associated comorbidities with deaths of COVID-19 patients.

Conclusion: Patients with diabetes and its associated comorbidities need more monitoring if get SARS-Cov-2 infection to reduce deaths.

Keywords: Covid-19 patients; Diabetes; Meta-analysis; Mortality.

Publication types

Review