Deep learning and Gaussian Mixture Modelling clustering mix. A new approach for fetal morphology view plane differentiation

J Biomed Inform. 2023 Jul:143:104402. doi: 10.1016/j.jbi.2023.104402. Epub 2023 May 20.

Abstract

The last three years have been a game changer in the way medicine is practiced. The COVID-19 pandemic changed the obstetrics and gynecology scenery. Pregnancy complications, and even death, are preventable due to maternal-fetal monitoring. A fast and accurate diagnosis can be established by a doctor + Artificial Intelligence combo. The aim of this paper is to propose a framework designed as a merger between Deep learning algorithms and Gaussian Mixture Modelling clustering applied in differentiating between the view planes of a second trimester fetal morphology scan. The deep learning methods chosen for this approach were ResNet50, DenseNet121, InceptionV3, EfficientNetV2S, MobileNetV3Large, and Xception. The framework establishes a hierarchy of the component networks using a statistical fitness function and the Gaussian Mixture Modelling clustering method, followed by a synergetic weighted vote of the algorithms that gives the final decision. We have tested the framework on two second trimester morphology scan datasets. A thorough statistical benchmarking process has been provided to validate our results. The experimental results showed that the synergetic vote of the framework outperforms the vote of each stand-alone deep learning network, hard voting, soft voting, and bagging strategy.

Keywords: Deep learning; Fetal morphology; Performance analysis; Statistical assessment; Weighted voting.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Artificial Intelligence
  • COVID-19*
  • Cluster Analysis
  • Deep Learning*
  • Female
  • Humans
  • Pandemics
  • Pregnancy