P-glycoprotein efflux transporter: a key to pharmacokinetic modeling for methadone clearance in fetuses
Front Pharmacol
.
2023 May 4:14:1182571.
doi: 10.3389/fphar.2023.1182571.
eCollection 2023.
Authors
Harvey Ho
1
,
En Zhang
2
Affiliations
1
Auckland Bioengineering Institute, The University of Auckland, Auckland, New Zealand.
2
Chongqing Food and Drug Control Institute, Chongqing, China.
PMID:
37214474
PMCID:
PMC10192552
DOI:
10.3389/fphar.2023.1182571
No abstract available
Keywords:
P-glycoprotein; PBPK; methadone; model; opioids.
Grants and funding
HH and EZ acknowledge the funding support of Chongqing Science and Technology Bureau (Grant number: cstc2022jxjl0299).