Neurological manifestation in COVID-19 disease with neuroimaging studies

Sadegh Ghaderi; Mahsa Olfati; Majid Ghaderi; Hojatollah Hadizadeh; Ghazal Yazdanpanah; Zahra Khodadadi; Asra Karami; Zahra Papi; Negar Abdi; Seyedeh Shadi Sharif Jalali; Rahim Khatyal; Shabnam Banisharif; Fatemeh Bahari; Marziyeh Zarasvandnia; Sana Mohammadi; Mahdi Mohammadi

Neurological manifestation in COVID-19 disease with neuroimaging studies

Am J Neurodegener Dis. 2023 Apr 15;12(2):42-84. eCollection 2023.

Authors

Sadegh Ghaderi¹, Mahsa Olfati², Majid Ghaderi³, Hojatollah Hadizadeh², Ghazal Yazdanpanah⁴, Zahra Khodadadi⁵, Asra Karami⁶, Zahra Papi⁷, Negar Abdi⁸, Seyedeh Shadi Sharif Jalali⁹, Rahim Khatyal¹⁰, Shabnam Banisharif⁷, Fatemeh Bahari¹¹, Marziyeh Zarasvandnia¹², Sana Mohammadi¹³, Mahdi Mohammadi¹⁴

Affiliations

¹ Department of Neuroscience and Addiction Studies, School of Advanced Technologies in Medicine, Tehran University of Medical Sciences Tehran, Iran.
² Department of Radiology and Nuclear Medicine, School of Paramedical, Kermanshah University of Medical Sciences Kermanshah, Iran.
³ Radiology Technology Department, School of Paramedicine, Shahid Beheshti University of Medical Sciences Tehran, Iran.
⁴ Department of Medical Physics and Biomedical Engineering, School of Medicine, Babol University of Medical Sciences Babol, Iran.
⁵ Department of Radiology, School of Allied Medical Sciences, Shahrekord University of Medical Sciences Shahrekord, Iran.
⁶ Department of Medical Physics, School of Medicine, Iran University of Medical Sciences Tehran, Iran.
⁷ Department of Medical Physics, School of Medicine, Isfahan University of Medical Science Isfahan, Iran.
⁸ Department of Radiology, Faculty of Paramedical Sciences, Kurdistan University of Medical Sciences Sanandaj, lran.
⁹ Department of Medical Physics, School of Medicine, Kermanshah University of Medical Sciences Kermanshah, Iran.
¹⁰ Radiology Technology Department, School of Paramedicine, Tabriz University of Medical Sciences Tabriz, Iran.
¹¹ Department of Radiology, School of Medicine, Semnan University of Medical Sciences Semnan, Iran.
¹² Department of Radiologic Technology, Faculty of Paramedicine, Ahvaz Jundishapur University of Medical Sciences Ahvaz, Iran.
¹³ Department of Medical Sciences, School of Medicine, Iran University of Medical Sciences Tehran, Iran.
¹⁴ Department of Medical Physics and Biomedical Engineering, School of Medicine, Tehran University of Medical Sciences Tehran, Iran.

PMID: 37213710
PMCID: PMC10195392

Abstract

Objective: Magnetic resonance imaging (MRI) of the brain or spine examines the findings as well as the time interval between the onset of symptoms and other adverse effects in coronavirus disease that first appeared in 2019 (COVID-19) patients. The goal of this study is to look at studies that use neuroimaging to look at neurological and neuroradiological symptoms in COVID-19 patients.

Methods: We try to put together all of the research on how severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) causes neurological symptoms and cognitive-behavioral changes and give a full picture.

Results: We have categorized neuroimaging findings into subtitles such as: headache and dizziness; cerebrovascular complications after stroke; Intracerebral Hemorrhage (ICH); Cerebral Microbleeds (CMBs); encephalopathy; meningitis; encephalitis and myelitis; altered mental status (AMS) and delirium; seizure; neuropsychiatric symptoms; Guillain-Barre Syndrome (GBS) and its variants; smell and taste disorders; peripheral neuropathy; Mild Cognitive Impairment (MCI); and myopathy and myositis.

Conclusion: In this review study, we talked about some MRI findings that show how COVID-19 affects the nervous system based on what we found.

Keywords: COVID-19; cognitive-behavioral disorders; magnetic resonance imaging; neurological symptoms; neuropsychological symptoms.

Publication types

Review