Anaplasmosis-Induced Hemophagocytic Lymphohistiocytosis: A Case Report and Review of the Literature

Open Forum Infect Dis. 2023 Apr 19;10(5):ofad213. doi: 10.1093/ofid/ofad213. eCollection 2023 May.

Abstract

Cases of anaplasmosis have increased steadily and are appearing in states where it is less common. While symptoms are usually mild, in rare cases it can cause hemophagocytic lymphohistiocytosis. Here, we present a case of polymerase chain reaction-confirmed Anaplasma phagocytophilum with morulae on peripheral blood smear associated with biopsy-proven hemophagocytic lymphohistiocytosis.

Keywords: Anaplasma phagocytophilum; anaplasmosis; hemophagocytic lymphohistiocytosis; tick-borne.

Publication types

  • Case Reports