The retinal bacillary layer detachment: Clinical features and outcomes in posterior uveitis

I Hernanz; A Moll-Udina; A Garcia-Tirado; M Garcia-Fernandez; R Gutierrez-Ezquerro; C Garcia-Arumi; V Llorenç; C Cuadros; A Fonollosa; M Sainz-de-la-Maza; A Adán

doi:10.1016/j.jfo.2022.12.031

The retinal bacillary layer detachment: Clinical features and outcomes in posterior uveitis

J Fr Ophtalmol. 2023 Oct;46(8):916-920. doi: 10.1016/j.jfo.2022.12.031. Epub 2023 May 18.

Authors

Affiliations

¹ Department of ophthalmology, Fundación Jiménez Diaz Hospital, Avenue Reyes Católicos 2, 28003 Madrid, Spain. Electronic address: ines.hernanz.ro@gmail.com.
² Clínic Hospital of Barcelona, Clínic Institute of Ophthalmology, University of Barcelona, Barcelona, Spain; Biomedical Research Institute August Pi I Sunyer (IDIBAPS), Barcelona, Spain.
³ Clínic Hospital of Barcelona, Clínic Institute of Ophthalmology, University of Barcelona, Barcelona, Spain.
⁴ Department of ophthalmology, Cruces University Hospital, Bilbao, Spain.
⁵ Department of ophthalmology, Oviedo University Hospital, Oviedo, Spain.
⁶ Departmentofophthalmology, Vall d'Hebron University Hospital, Barcelona, Spain.

PMID: 37210295
DOI: 10.1016/j.jfo.2022.12.031

Abstract

Purpose: To describe the clinical characteristics, presentation and response to treatment in posterior uveitis patients with bacillary layer detachment (BLD) seen on optical coherence tomography (OCT).

Materials and methods: Retrospective review of patients with posterior uveitis and SD-OCT scans consistent with BLD. Data collected included demographics, uveitic etiology, treatment and duration of follow-up. Outcome measures included macular volume, central subfoveal thickness and visual acuity.

Results: Sixteen patients (20 eyes) were included. Twelve were female (75%). The mean age was 43.68 ± 14.7 years. The most frequent etiology of the uveitis was Vogt-Koyanagi-Harada (VKH) disease (n=10), followed by sympathetic ophthalmia (n=2). BLD was bilateral in four patients. Eight patients were treated with intravenous methylprednisolone boluses. Immunosuppressive therapies were required in 8 patients. The mean follow-up was 70 months (range: 2.0-216.0).

Conclusion: BLD was observed in a series of posterior uveitis cases of various etiologies, showing functional and structural resolution with treatment in most cases.

Keywords: Bacillary layer; Choroiditis; Choroïdite; Couche bacillaire; Optical coherence tomography; Posterior uveitis; Tomographie de cohérence optique; Uvéite postérieure; Vogt-Koyanagi-Harada.