A Long-Term Survival Case of Coronary Artery Intimal Sarcoma

Int Heart J. 2023 May 31;64(3):483-486. doi: 10.1536/ihj.22-578. Epub 2023 May 16.

Abstract

Primary cardiac sarcomas are rare diseases with very poor prognoses. In this report, we present a case of coronary artery intimal sarcoma in a patient who survived for a long time after diagnosis. A 57-year-old female underwent percutaneous coronary intervention of the right coronary artery due to acute myocardial infarction caused by thrombotic occlusion and was diagnosed as having coronary artery intimal sarcoma. She underwent surgical resection and coronary artery bypass surgery of the artery, cryothermy coagulation, and postoperative adjuvant chemotherapy for 1 year. After 3 years, focal recurrence was detected in the caudal region of the left ventricular inferior wall. Radiotherapy was performed. The tumor shrank significantly after radiotherapy. Four years later, there was no significant abnormal uptake on positron-emission tomography/computed tomography. At 7 years after diagnosis, when this case report was submitted, the patient was alive and her performance had maintained a good status. Intimal sarcoma occurring in a coronary artery is extremely rare. The efficacy of treatments for cardiac intimal sarcoma, which include surgical resection, chemotherapy and radiotherapy, has been reported to be limited. To the best of our knowledge, this is the first report of a case of coronary artery intimal sarcoma with long-term survival after comprehensive therapies including surgical resection and radiotherapy.

Keywords: Chemotherapy; Cryothermy coagulation; Radiotherapy.

Publication types

  • Case Reports

MeSH terms

  • Coronary Vessels* / pathology
  • Female
  • Humans
  • Middle Aged
  • Positron Emission Tomography Computed Tomography
  • Prognosis
  • Sarcoma* / diagnosis
  • Sarcoma* / pathology
  • Sarcoma* / therapy