Inside PD-1/PD-L1,2 with their inhibitors

Eur J Med Chem. 2023 Aug 5:256:115465. doi: 10.1016/j.ejmech.2023.115465. Epub 2023 May 6.

Abstract

This review summarizes current knowledge in the development of immune checkpoint inhibitors, including antibodies and small molecules.

Keywords: Immune check point; Inhibitors; PD-L1; PD-L2; PD1.

Publication types

  • Review

MeSH terms

  • Antibodies
  • B7-H1 Antigen*
  • Programmed Cell Death 1 Receptor*

Substances

  • Programmed Cell Death 1 Receptor
  • B7-H1 Antigen
  • Antibodies