Recent progress of TP/NIR fluorescent probes for metal ions

Yahui Chen; Shiyue Zheng; Myung Hwa Kim; Xiaoqiang Chen; Juyoung Yoon

doi:10.1016/j.cbpa.2023.102321

Recent progress of TP/NIR fluorescent probes for metal ions

Curr Opin Chem Biol. 2023 Aug:75:102321. doi: 10.1016/j.cbpa.2023.102321. Epub 2023 May 15.

Authors

Yahui Chen¹, Shiyue Zheng², Myung Hwa Kim¹, Xiaoqiang Chen², Juyoung Yoon³

Affiliations

¹ Department of Chemistry and Nanoscience, Ewha Womans University, Seoul, 03760, South Korea; New and Renewable Energy Research Center, Ewha Womans University, Seoul, 03760, South Korea.
² State Key Laboratory of Materials-Oriented Chemical Engineering, College of Chemical Engineering, Jiangsu National Synergetic Innovation Center for Advanced Materials (SICAM), Nanjing Tech University, Nanjing, 211816, China.
³ Department of Chemistry and Nanoscience, Ewha Womans University, Seoul, 03760, South Korea. Electronic address: jyoon@ewha.ac.kr.

PMID: 37196449
DOI: 10.1016/j.cbpa.2023.102321

Abstract

Metal ions are of significance in various pathological and physiological processes. As such, it is crucial to monitor their levels in organisms. Two-photon (TP) and near-infrared (NIR) fluorescence imaging has been utilized to monitor metal ions because of minimal background interference, deeper tissue depth penetration, lower tissue self-absorption, and reduced photodamage. In this review, we briefly summarize recent progress from 2020 to 2022 of TP/NIR organic fluorescent probes and inorganic sensors in the detection of metal ions. Additionally, we present an outlook for the development of TP/NIR probes for bio-imaging, diagnosis of diseases, imaging-guided therapy, and activatable phototherapy.

Keywords: Fluorescence imaging; Fluorescent probes; Metal ions; Near-infrared; Two-photon.

Publication types

Review
Research Support, Non-U.S. Gov't

MeSH terms

Fluorescent Dyes*
Ions
Metals*
Optical Imaging

Substances

Fluorescent Dyes
Metals
Ions