Inferior implant of XEN63 Gel stent in a refractory open-angle glaucoma due to silicone oil tamponade: A case report

Eur J Ophthalmol. 2024 Jan;34(1):NP27-NP31. doi: 10.1177/11206721231172231. Epub 2023 May 16.

Abstract

Background: To discuss the efficacy of an inferior implant of XEN 63 gel stent in a patient with refractory glaucoma after trabeculectomy failure and vitreoretinal surgery with silicone oil tamponade.

Case description: We report the case of a 73-year-old man with a history of refractory open glaucoma with trabeculectomy failure. He experienced recurrent retinal detachments with silicone oil tamponade, with uncontrolled intra-ocular pressure (IOP) after silicone oil removal. Due to the presence of oil emulsion in the anterior chamber, the chosen location for XEN 63 implantation was the infero-temporal quadrant. Mild hyphema and vitreous hemorrhage were seen post-operatively, but were self-limiting. At week 1, the intraocular pressure was 8 mmHg with a well-formed bleb seen in anterior segment optical coherence tomography (AS-OCT). At 6 month follow up, the patient maintained a IOP of 12 mmHg without topical hypotensive drugs. Slit lamp examination revealed a widespread, developed bleb with no signs of inflammation.

Conclusion: In this case of refractory glaucoma in a vitrectomized eye with previous oil tamponade, the inferior placement of the XEN 63 gel stent delivered an adequate intraocular pressure even at 6-months follow up, with a diffuse functional infero-nasal bleb seen with AS-OCT.

Keywords: XEN 63 gel stent; anterior segment optical coherence tomography; refractory glaucoma; silicone oil tamponade.

Publication types

  • Case Reports

MeSH terms

  • Aged
  • Glaucoma Drainage Implants* / adverse effects
  • Glaucoma* / surgery
  • Glaucoma, Open-Angle* / surgery
  • Humans
  • Intraocular Pressure
  • Male
  • Silicone Oils / adverse effects
  • Stents / adverse effects

Substances

  • Silicone Oils