Effectiveness of Heterologous COVID-19 Vaccine Booster in Korean Elderly Population, 2022

J Korean Med Sci. 2023 May 15;38(19):e143. doi: 10.3346/jkms.2023.38.e143.

Abstract

We conducted a cohort study to assess vaccine effectiveness (VE) of coronavirus disease 2019 vaccine combinations on severe acute respiratory syndrome coronavirus 2 critical infection and death among elderly population in Korea. From January to August 2022, VE against death for 4 doses mRNA recipients was 96.1%, whereas 1-dose viral vector + 3-dose mRNA recipients had VE of 90.8%.

Keywords: COVID-19; Coronavirus; Elderly; SARS-CoV-2.

MeSH terms

  • Aged
  • COVID-19 Vaccines
  • COVID-19* / prevention & control
  • Cohort Studies
  • Humans
  • RNA, Messenger
  • Republic of Korea

Substances

  • COVID-19 Vaccines
  • RNA, Messenger

Supplementary concepts

  • COVID-19 vaccine booster shot