Botanical characteristics, chemical components, biological activity, and potential applications of mangosteen

Chenchen Bi; Hang Xu; Jingru Yu; Zhinan Ding; Zheng Liu

doi:10.7717/peerj.15329

Botanical characteristics, chemical components, biological activity, and potential applications of mangosteen

PeerJ. 2023 May 9:11:e15329. doi: 10.7717/peerj.15329. eCollection 2023.

Authors

Chenchen Bi^#^{1

2}, Hang Xu^#¹, Jingru Yu¹, Zhinan Ding², Zheng Liu²

Affiliations

¹ Department of Clinical Medicine, School of Medicine, Shaoxing University, Shaoxing, Zhejiang, PR China.
² Department of Pharmacology, School of Medicine, Shaoxing University, Shaoxing, Zhejiang, PR China.

^# Contributed equally.

Abstract

Garcinia mangostana L. (Mangosteen), a functional food, belongs to the Garcinaceae family and has various pharmacological effects, including anti-oxidative, anti-inflammatory, anticancer, antidiabetic, and neuroprotective effects. Mangosteen has abundant chemical constituents with powerful pharmacological effects. After searching scientific literature databases, including PubMed, Science Direct, Research Gate, Web of Science, VIP, Wanfang, and CNKI, we summarized the traditional applications, botanical features, chemical composition, and pharmacological effects of mangosteen. Further, we revealed the mechanism by which it improves health and treats disease. These findings provide a theoretical basis for mangosteen's future clinical use and will aid doctors and researchers who investigate the biological activity and functions of food.

Keywords: Application; Biological activity; Botanical features; Mangosteen; Molecular mechanisms; Phytochemistry.

Publication types

Research Support, Non-U.S. Gov't

MeSH terms

Anti-Inflammatory Agents / pharmacology
Fruit / chemistry
Functional Food
Garcinia mangostana* / chemistry
Plant Extracts* / pharmacology

Substances

Plant Extracts
Anti-Inflammatory Agents

Grants and funding

This work was funded by Zhejiang Provincial First Courses of Medical Biochemistry (No. 20220646) and Yue Di Element General Curriculum Project of Shaoxing Higher Education Institutions (No. 20225306). The funders had no role in study design, data collection and analysis, decision to publish, or preparation of the manuscript.