A Rare Case of Primary Duodenal Plasmacytoma: An Incidental Finding

Cureus. 2023 Apr 9;15(4):e37342. doi: 10.7759/cureus.37342. eCollection 2023 Apr.

Abstract

Solitary extramedullary plasmacytoma (SEP) is a rare tumor due to the monoclonal proliferation of plasma cells without bone marrow involvement. Plasmacytomas are frequently encountered in bone or soft tissue but rarely occur in the gastrointestinal (GI) tract. They can present with a multitude of symptoms depending on their site. This report describes a case of SEP diagnosed as a duodenal ulcer (DU) during esophagogastroduodenoscopy (EGD) for iron deficiency anemia.

Keywords: extramedullary plasmacytoma; gastrointestinal bleed; multiple myeloma; plasma cell neoplasm; solitary extramedullary plasmacytoma.

Publication types

  • Case Reports