Predictive factors of recurrence in spontaneous bacterial peritonitis in Tunisian patients with cirrhosis

Manel Moalla; Nour Elleuch; Wafa Dahmani; Aya Hammami; Wafa Ben Ameur; Aida Ben Slama; Ahlem Brahem; Salem Ajmi; Mehdi Ksiaa; Hanen Jaziri; Ali Jmaa

doi:10.2144/fsoa-2023-0016

Predictive factors of recurrence in spontaneous bacterial peritonitis in Tunisian patients with cirrhosis

Future Sci OA. 2023 Apr 17;9(5):FSO857. doi: 10.2144/fsoa-2023-0016. eCollection 2023 Jun.

Authors

Affiliation

¹ Department of gastroenterology, Sahloul University Hospital, Sousse, 4054, Tunisia.

Abstract

Introduction: Recurrent spontaneous bacterial peritonitis (SBP) in patients with cirrhosis is associated with poor prognosis.

Aim: To assess the prevalence and the risk factors for recurrence and to evaluate its impact on the prognosis.

Materials & methods: We conducted a retrospective study including patients with cirrhosis having a first episode of SBP.

Results: A recurrence of SBP was identified in 43.4% of the patients who survived after a first episode of SBP. The mean time to onset of the first SBP recurrence from the first episode was 32 days. Recurrence factors were endoscopic hypertensive signs, a positive ascites culture, diarrhea and the MELD score.

Conclusion: There was no impact on survival of recurrent SBP compared with the first SBP episode.

Keywords: Tunisia; cirrhosis; prognosis; recurrence; spontaneous bacterial peritonitis.

Plain language summary

Recurrent spontaneous bacterial peritonitis (SBP) in patients with cirrhosis is associated with poor prognosis. The aims of this study were to assess the prevalence and the risk factors for recurrence and to evaluate its impact on the prognosis. Thus, we conducted a retrospective study including patients with cirrhosis having a first episode of SBP. A recurrence of SBP was identified in 43.4% of the patients who survived after a first episode of SBP. Recurrence factors were endoscopic hypertensive signs, a positive ascites culture, diarrhea and the MELD score.