GluD receptors are functional ion channels

Janesh Kumar; Gabriela K Popescu; Stephanie C Gantz

doi:10.1016/j.bpj.2023.05.012

GluD receptors are functional ion channels

Biophys J. 2023 Jun 20;122(12):2383-2395. doi: 10.1016/j.bpj.2023.05.012. Epub 2023 May 12.

Authors

Janesh Kumar¹, Gabriela K Popescu², Stephanie C Gantz³

Affiliations

¹ Laboratory of Membrane Protein Biology, Council of Scientific and Industrial Research (CSIR)-Centre for Cellular and Molecular Biology, Hyderabad, Telangana, India; Academy of Scientific and Innovative Research (AcSIR), Ghaziabad, India.
² Department of Biochemistry, Jacobs School of Medicine and Biomedical Sciences, University of Buffalo, SUNY, Buffalo, New York.
³ Department of Molecular Physiology and Biophysics, Carver College of Medicine, University of Iowa, Iowa City, Iowa; Iowa Neuroscience Institute, University of Iowa, Iowa City, Iowa. Electronic address: stephanie-gantz@uiowa.edu.

PMID: 37177782
PMCID: PMC10323023 (available on 2024-06-20)
DOI: 10.1016/j.bpj.2023.05.012

Abstract

In this article, we review contemporary evidence that GluD receptors are functional ion channels whose depolarizing currents contribute to their biological functions, akin to all other members of the ionotropic glutamate receptor (iGluR) family.

Publication types

Review
Research Support, Non-U.S. Gov't

MeSH terms

Receptors, Ionotropic Glutamate*

Substances

Receptors, Ionotropic Glutamate

Abstract

Publication types

MeSH terms

Substances

Grants and funding