Factors associated with mortality in patients hospitalized for COVID-19 admitted to a tertiary hospital in Lambayeque, Peru, during the first wave of the pandemic

PLoS One. 2023 May 11;18(5):e0285133. doi: 10.1371/journal.pone.0285133. eCollection 2023.

Abstract

Introduction: COVID-19 caused by Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) has spread worldwide, becoming a long-term pandemic.

Objectives: To analyze the factors associated with mortality in patients hospitalized for COVID-19 in a tertiary hospital in the Lambayeque region of Peru.

Methods: A retrospective cohort study of patients with a diagnosis of COVID-19, hospitalized in a hospital in northern Peru, was conducted from March to September 2020.

Results: Of the 297 patients studied, 69% were women, the mean age was 63.99 years (SD = ±15.33 years). Hypertension was the most frequent comorbidity (36.67%), followed by diabetes mellitus (24.67%) and obesity (8.33%). The probability of survival at 3 days of ICU stay was 65.3%, at 7 days 24.2%, and 0% on day 14. Risk factors associated with mortality in patients hospitalized for COVID-19 are age, male sex, tachypnea, low systolic blood pressure, low peripheral oxygen saturation, impaired renal function, elevated IL-6 and elevated D-dimer.

Conclusions: Mortality in hospitalized patients with COVID-19 was 51.18 per 100 persons, Mortality was found to be associated with hypertension, type of infiltrating, and sepsis.

MeSH terms

  • COVID-19* / epidemiology
  • Female
  • Hospital Mortality
  • Hospitalization
  • Humans
  • Hypertension* / epidemiology
  • Male
  • Middle Aged
  • Pandemics
  • Peru / epidemiology
  • Retrospective Studies
  • Risk Factors
  • SARS-CoV-2
  • Tertiary Care Centers

Associated data

  • figshare/10.6084/m9.figshare.21664172.v1

Grants and funding

This research received no external funding.