Extraction, Labeling, Clustering, and Semantic Mapping of Segments From Clinical Notes

IEEE Trans Nanobioscience. 2023 Oct;22(4):781-788. doi: 10.1109/TNB.2023.3275195. Epub 2023 Oct 3.

Abstract

This work is motivated by the scarcity of tools for accurate, unsupervised information extraction from unstructured clinical notes in computationally underrepresented languages, such as Czech. We introduce a stepping stone to a broad array of downstream tasks such as summarisation or integration of individual patient records, extraction of structured information for national cancer registry reporting or building of semi-structured semantic patient representations that can be used for computing patient embeddings. More specifically, we present a method for unsupervised extraction of semantically-labeled textual segments from clinical notes and test it out on a dataset of Czech breast cancer patients, provided by Masaryk Memorial Cancer Institute (the largest Czech hospital specialising exclusively in oncology). Our goal was to extract, classify (i.e. label) and cluster segments of the free-text notes that correspond to specific clinical features (e.g., family background, comorbidities or toxicities). Finally, we propose a tool for computer-assisted semantic mapping of segment types to pre-defined ontologies and validate it on a downstream task of category-specific patient similarity. The presented results demonstrate the practical relevance of the proposed approach for building more sophisticated extraction and analytical pipelines deployed on Czech clinical notes.

MeSH terms

  • Breast Neoplasms*
  • Cluster Analysis
  • Female
  • Humans
  • Information Storage and Retrieval
  • Semantics*