Different autoantibodies can be detected in patients with coronavirus disease 2019 (COVID-19). It is reported that severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection could induce autoimmune diseases (AID), including children's multisystem inflammatory syndrome (MIS-C), Guillain Barre syndrome (GBS), Autoimmune hemolytic anemia (AIHA), immune thrombocytopenia (ITP) and thyroid autoimmune diseases. This article mainly reviews the similarities between COVID-19 and AID, the possibility of COVID-19 inducing AID, the risk of AID patients infected or vaccinated against COVID-19. The purpose is to provide strategies for the prevention, management and treatment of AID during the epidemic.
新型冠状病毒肺炎（COVID-19）患者体内可检测到多种自身抗体，严重急性呼吸综合征冠状病毒2型（SARS-CoV-2）感染可诱发自身免疫性疾病（AID）。目前相关研究报道病例有儿童多系统炎症综合征（MIS-C）、格林-巴利综合征（GBS）、自身免疫性溶血性贫血（AIHA）、免疫性血小板减少症（ITP）和甲状腺自身免疫性疾病等。本文主要从COVID-19与AID免疫反应的相似性、COVID-19诱发的AID、AID患者感染SARS-CoV-2及接种新冠疫苗的风险等方面进行阐述，为AID的预防管理和治疗提供策略和思路。.