Osteoarticular infections at a pediatric emergency core hospital in Japan

J Med Invest. 2023;70(1.2):236-240. doi: 10.2152/jmi.70.236.

Abstract

Objectives: Osteomyelitis (OM) and septic arthritis (SA) in childhood might cause complications, sequelae, or even death if diagnosis and treatment are delayed. Here, we examined the outcomes of OM/SA at a pediatric emergency core hospital in Japan.

Methods: This was a single-center, retrospective, observational cohort study at a pediatric emergency core hospital in Japan. Pediatric outpatients who underwent magnetic resonance imaging at the hospital in the period 2012?2020 were recruited. Primary outcomes were sequelae, recurrent symptoms, chronicity, and death.

Results: Fifteen OM/SA patients (9 OM, 4 SA, 2 OM+SA) were recruited. The identified major pathogens included methicillin-susceptible Staphylococcus aureus (40.0 %, n=6) and methicillin-resistant S. aureus (13.3 %, n=2). Mean time from onset to first hospital visit, hospitalization, and initiation of effective antibiotics was 2 days, 3.9?±?1.8 days, and 4.9±2.2 days, respectively. All OM/SA patients recovered without complications or sequelae.

Conclusions: In this study, all patients with OM/SA showed a good prognosis. Despite the small sample size, this pilot study suggests that the pediatric emergency core system in Japan provides early treatment and a good prognosis for patients diagnosed with OM/SA. J. Med. Invest. 70 : 236-240, February, 2023.

Keywords: osteomyelitis; pediatric emergency system; retrospective cohort study; septic arthritis.

Publication types

  • Observational Study

MeSH terms

  • Anti-Bacterial Agents / therapeutic use
  • Arthritis, Infectious* / complications
  • Arthritis, Infectious* / diagnosis
  • Arthritis, Infectious* / therapy
  • Child
  • Disease Progression
  • Humans
  • Japan / epidemiology
  • Methicillin-Resistant Staphylococcus aureus*
  • Osteomyelitis* / complications
  • Osteomyelitis* / diagnosis
  • Osteomyelitis* / therapy
  • Pilot Projects
  • Retrospective Studies
  • Staphylococcal Infections* / complications
  • Staphylococcal Infections* / diagnosis
  • Staphylococcal Infections* / drug therapy

Substances

  • Anti-Bacterial Agents