A new abietane diterpenoid from Lycopodium complanatum

J Asian Nat Prod Res. 2023 Dec;25(12):1217-1222. doi: 10.1080/10286020.2023.2209567. Epub 2023 May 10.

Abstract

A new abietane diterpenoid, 1β, 11-epoxyabieta-12-hydroxy-8, 11, 13-triene-7-one (1), along with three known compounds (2-4), was isolated from Lycopodium complanatum. Their structures were confirmed by the analysis of 1D, 2D NMR and HRESIMS data, and comparison with previous spectral data. All compounds were tested for inhibitory activities against A549, HepG2 and MCF-7 tumor cell lines. [Figure: see text].

Keywords: Lycopodiaceae; Lycopodium complanatum; abietane diterpenoids; cytotoxic activities.

MeSH terms

  • Abietanes / chemistry
  • Abietanes / pharmacology
  • Antineoplastic Agents, Phytogenic* / chemistry
  • Antineoplastic Agents, Phytogenic* / pharmacology
  • Cell Line, Tumor
  • Humans
  • Lycopodium* / chemistry
  • MCF-7 Cells
  • Molecular Structure

Substances

  • Abietanes
  • Antineoplastic Agents, Phytogenic