Elastic band resistance combined with modified Thai yoga exercise to alleviate oxidative stress and airway inflammation in type 2 diabetes mellitus

Tichanon Promsrisuk; Ratchaniporn Kongsui; Napatr Sriraksa; Orachorn Boonla; Arunrat Srithawong

doi:10.12965/jer.2346040.020

Elastic band resistance combined with modified Thai yoga exercise to alleviate oxidative stress and airway inflammation in type 2 diabetes mellitus

J Exerc Rehabil. 2023 Apr 27;19(2):114-125. doi: 10.12965/jer.2346040.020. eCollection 2023 Apr.

Authors

Tichanon Promsrisuk^{1

2}, Ratchaniporn Kongsui¹, Napatr Sriraksa^{1

2}, Orachorn Boonla^{3

4}, Arunrat Srithawong⁵

Affiliations

¹ Division of Physiology, School of Medical Sciences, University of Phayao, Phayao, Thailand.
² Unit of Excellence in the Pulmonary and Cardiovascular Health Care, University of Phayao, Phayao, Thailand.
³ Faculty of Allied Health Sciences, Burapha University, Chonburi, Thailand.
⁴ Exercise and Nutrition Innovation and Sciences Research Unit, Burapha University, Chonburi, Thailand.
⁵ Department of Physical Therapy, School of Allied Health Sciences, University of Phayao, Phayao, Thailand.

Abstract

The objective of this study was to investigate the effects of the combination of elastic band resistance exercise (EBRE) with modified Thai yoga on the alleviation of blood glucose and oxidative stress in type 2 diabetes mellitus (T2DM). Forty-two patients with T2DM were enrolled and allocated to an exercise or control group (n=21/group). The exercise group participated in EBRE combination with modified Thai yoga for 40 min, 5 days/wk, for 12 consecutive weeks. Blood glucose, oxidative stress markers, antioxidants, pulmonary function, respiratory muscle strength, and airway inflammation were measured before and after the 12 weeks. The results showed that the exercise group had a significant reduction in fasting blood glucose and glycated hemoglobin. Moreover, T2DM patients in the exercise group showed a significant reduction in plasma malondialdehyde, while superoxide dismutase and catalase were significantly increased. The exercise group also observed a significant improvement in pulmonary function; forced expiratory volume in the first second (FEV₁), forced vital capacity (FVC), FEV₁/FVC, peak expiratory flow, and forced midexpiratory flow as well as respiratory muscle strength. Interestingly, the combination of EBRE with modified Thai yoga markedly improved airway inflammation through the reduction in fractional exhaled nitric oxide. In conclusion, these findings suggest that the combination of EBRE with modified Thai yoga improves blood glucose, oxidative stress, antioxidants, pulmonary function, respiratory muscle strength, and airway inflammation in T2DM patients. Hence, it could be considered as a possible exercise program for T2DM patients.

Keywords: Diabetes mellitus; Elastic band resistance; Lung function; Oxidative stress; Yoga.

Grants and funding

This research was supported by the Thailand Science Research and Innovation Fund and the University of Phayao (Grant No. FF64-UoE023 and FF66-RIM049).